Authors:
Macdonald, SJF
Dowle, MD
Harrison, LA
Spooner, JE
Shah, P
Johnson, MR
Inglis, GGA
Clarke, GDE
Belton, DJ
Smith, RA
Molloy, CR
Dixon, M
Murkitt, G
Godward, RE
Skarzynski, T
Singh, OMP
Kumar, KA
Hodgson, ST
McDonald, E
Hardy, GW
Finch, H
Humphreys, DC
Fleetwood, G
Citation: Sjf. Macdonald et al., Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams (vol 11, pg 243, 2001), BIOORG MED, 11(9), 2001, pp. 1249-1249
Authors:
Mcdonold, SJF
Dowle, MD
Harrison, LA
Shah, P
Johnson, MR
Inglis, GGA
Clarke, GDE
Smith, RA
Humphreys, D
Molloy, CR
Amour, A
Dixon, M
Murkitt, G
Godward, RE
Padfield, T
Skarzynski, T
Singh, OMP
Kumar, KA
Fleetwood, G
Hodgson, ST
Hardy, GW
Fincha, H
Citation: Sjf. Mcdonold et al., The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil Elastase - GW311616A a development candidate, BIOORG MED, 11(7), 2001, pp. 895-898
Authors:
Macdonald, SJF
Dowle, MD
Harrison, LA
Spooner, JE
Shah, P
Johnson, MR
Inglis, GGA
Clarke, GDE
Belton, DJ
Smith, RA
Molloy, CR
Dixon, M
Murkitt, G
Godward, RE
Skarzynski, T
Singh, OMP
Kumar, KA
Hodgson, ST
McDonald, E
Hardy, GW
Finch, H
Citation: Sjf. Macdonald et al., Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams, BIOORG MED, 11(2), 2001, pp. 243-246
Authors:
Young, RJ
Beams, RM
Carter, K
Clark, HAR
Coe, DM
Chambers, CL
Davies, PI
Dawson, J
Drysdale, MJ
Franzman, KW
French, C
Hodgson, ST
Hodson, HF
Kleanthous, S
Rider, P
Sanders, D
Sawyer, DA
Scott, KJ
Shearer, BG
Stocker, R
Smith, S
Tackley, MC
Knowles, RG
Citation: Rj. Young et al., Inhibition of inducible nitric oxide synthase by acetamidine derivatives of hetero-substituted lysine and homolysine, BIOORG MED, 10(6), 2000, pp. 597-600
Authors:
MacDonald, SJF
Clarke, GDE
Dowle, MD
Harrison, LA
Hodgson, ST
Inglis, GGA
Johnson, MR
Shah, P
Upton, RJ
Walls, SB
Citation: Sjf. Macdonald et al., A flexible, practical, and stereoselective synthesis of enantiomerically pure trans-5-oxohexahydropyrrolo[3,2-b]pyrroles (pyrrolidine-trans-lactams),a new class of serine protease inhibitors, using acyliminium methodology, J ORG CHEM, 64(14), 1999, pp. 5166-5175