AAAAAA

   
Results: 1-25 | 26-30
Results: 1-25/30
RAPID IDENTIFICATION OF SUBTYPE-SELECTIVE AGONISTS OF THE SOMATOSTATIN RECEPTOR THROUGH COMBINATORIAL CHEMISTRY
Authors: ROHRER SP BIRZIN ET MOSLEY RT BERK SC HUTCHINS SM SHEN DM XIONG YS HAYES EC PARMAR RM FOOR F MITRA SW DEGRADO SJ SHU M KLOPP JM CAI SJ BLAKE A CHAN WWS PASTERNAK A YANG LH PATCHETT AA SMITH RG CHAPMAN KT SCHAEFFER JM
Citation: Sp. Rohrer et al., RAPID IDENTIFICATION OF SUBTYPE-SELECTIVE AGONISTS OF THE SOMATOSTATIN RECEPTOR THROUGH COMBINATORIAL CHEMISTRY, Science, 282(5389), 1998, pp. 737-740
SEARCHING FOR A WINNING COMBINATION - EDITORIAL OVERVIEW
Authors: JOYCE GF STILL WC CHAPMAN KT
Citation: Gf. Joyce et al., SEARCHING FOR A WINNING COMBINATION - EDITORIAL OVERVIEW, CURRENT OPINION IN CHEMICAL BIOLOGY, 1(1), 1997, pp. 3-4
A COMBINATORIAL APPROACH FOR DETERMINING PROTEASE SPECIFICITIES - APPLICATION TO INTERLEUKIN-1-BETA CONVERTING-ENZYME (ICE)
Authors: RANO TA TIMKEY T PETERSON EP ROTONDA J NICHOLSON DW BECKER JW CHAPMAN KT THORNBERRY NA
Citation: Ta. Rano et al., A COMBINATORIAL APPROACH FOR DETERMINING PROTEASE SPECIFICITIES - APPLICATION TO INTERLEUKIN-1-BETA CONVERTING-ENZYME (ICE), Chemistry & biology, 4(2), 1997, pp. 149-155
SPATIALLY ARRAYED MIXTURE (SPAM) TECHNOLOGY - SYNTHESIS OF 2-DIMENSIONALLY INDEXED ORTHOGONAL COMBINATORIAL LIBRARIES
Authors: BERK SC CHAPMAN KT
Citation: Sc. Berk et Kt. Chapman, SPATIALLY ARRAYED MIXTURE (SPAM) TECHNOLOGY - SYNTHESIS OF 2-DIMENSIONALLY INDEXED ORTHOGONAL COMBINATORIAL LIBRARIES, Bioorganic & medicinal chemistry letters, 7(7), 1997, pp. 837-842
SOLID-PHASE SYNTHESIS OF A N-CARBOXYALKYL TRIPEPTIDE COMBINATORIAL LIBRARY
Authors: ESSER CK KEVIN NJ YATES NA CHAPMAN KT
Citation: Ck. Esser et al., SOLID-PHASE SYNTHESIS OF A N-CARBOXYALKYL TRIPEPTIDE COMBINATORIAL LIBRARY, Bioorganic & medicinal chemistry letters, 7(20), 1997, pp. 2639-2644
SOLID-PHASE SYNTHESIS OF SPIROINDOLINE
Authors: CHENG Y CHAPMAN KT
Citation: Y. Cheng et Kt. Chapman, SOLID-PHASE SYNTHESIS OF SPIROINDOLINE, Tetrahedron letters, 38(9), 1997, pp. 1497-1500
INHIBITION OF STROMELYSIN-1 (MMP-3) BY P-1'-BIPHENYLYLETHYL CARBOXYALKYL DIPEPTIDES
Authors: ESSER CK BUGIANESI RL CALDWELL CG CHAPMAN KT DURETTE PL GIROTRA NN KOPKA IE LANZA TJ LEVORSE DA MACCROSS M OWENS KA PONPIPOM MM SIMEONE JP HARRISON RK NIEDZWIECKI L BECKER JW MARCY AI AXEL MG CHRISTEN AJ MCDONNELL J MOORE VL OLSZEWSKI JM SAPHOS C VISCO DM SHEN F COLLETTI A KRIETER PA HAGMANN WK
Citation: Ck. Esser et al., INHIBITION OF STROMELYSIN-1 (MMP-3) BY P-1'-BIPHENYLYLETHYL CARBOXYALKYL DIPEPTIDES, Journal of medicinal chemistry, 40(6), 1997, pp. 1026-1040
A COMBINATORIAL APPROACH DEFINES SPECIFICITIES OF MEMBERS OF THE CASPASE FAMILY AND GRANZYME-B - FUNCTIONAL, RELATIONSHIPS ESTABLISHED FOR KEY MEDIATORS OF APOPTOSIS
Authors: THORNBERRY NA RANON TA PIETERSON EP RASPER DM TIMKEY T GARCIACALVO M HOUTZAGER VM NORDSTROM PA ROY S VAILLANCOURT JP CHAPMAN KT NICHOLSON DW
Citation: Na. Thornberry et al., A COMBINATORIAL APPROACH DEFINES SPECIFICITIES OF MEMBERS OF THE CASPASE FAMILY AND GRANZYME-B - FUNCTIONAL, RELATIONSHIPS ESTABLISHED FOR KEY MEDIATORS OF APOPTOSIS, The Journal of biological chemistry, 272(29), 1997, pp. 17907-17911
ORALLY-ACTIVE INHIBITORS OF STROMELYSIN-1 (MMP-3)
Authors: CHAPMAN KT DURETTE PL CALDWELL CG SPEROW KM NIEDZWIECKI LM HARRISON RK SAPHOS C CHRISTEN AJ OLSZEWSKI JM MOORE VL MACCOSS M HAGMANN WK
Citation: Kt. Chapman et al., ORALLY-ACTIVE INHIBITORS OF STROMELYSIN-1 (MMP-3), Bioorganic & medicinal chemistry letters, 6(7), 1996, pp. 803-806
INHIBITION OF MATRIX METALLOPROTEINASES BY P-1 SUBSTITUTED N-CARBOXYALKYL DIPEPTIDES
Authors: CHAPMAN KT WALES J SAHOO SP NIEDZWIECKI LM IZQUIERDOMARTIN M CHANG BC HARRISON RK STEIN RL HAGMANN WK
Citation: Kt. Chapman et al., INHIBITION OF MATRIX METALLOPROTEINASES BY P-1 SUBSTITUTED N-CARBOXYALKYL DIPEPTIDES, Bioorganic & medicinal chemistry letters, 6(3), 1996, pp. 329-332
PROTEOGLYCAN-DEGRADING ACTIVITY OF HUMAN STROMELYSIN-1 AND LEUKOCYTE ELASTASE IN RABBIT JOINTS - QUANTITATION OF PROTEOGLYCAN AND A STROMELYSIN-INDUCED HABR FRAGMENT OF AGGRECAN IN SYNOVIAL-FLUID AND CARTILAGE
Authors: OLSZEWSKI JM MOORE VL MCDONNELL J WILLIAMS H SAPHOS CA GREEN BG KNIGHT WB CHAPMAN KT HAGMANN WK DORN CP HALE JJ MUMFORD RA
Citation: Jm. Olszewski et al., PROTEOGLYCAN-DEGRADING ACTIVITY OF HUMAN STROMELYSIN-1 AND LEUKOCYTE ELASTASE IN RABBIT JOINTS - QUANTITATION OF PROTEOGLYCAN AND A STROMELYSIN-INDUCED HABR FRAGMENT OF AGGRECAN IN SYNOVIAL-FLUID AND CARTILAGE, Connective tissue research, 33(4), 1996, pp. 291-299
SOLID-PHASE SYNTHESIS OF ARYL AMINES
Authors: WILLOUGHBY CA CHAPMAN KT
Citation: Ca. Willoughby et Kt. Chapman, SOLID-PHASE SYNTHESIS OF ARYL AMINES, Tetrahedron letters, 37(40), 1996, pp. 7181-7184
SOLID-PHASE SYNTHESIS OF TETRAHYDROISOQUINOLINES AND TETRAHYDROIMIDAZOPYRIDINES
Authors: HUTCHINS SM CHAPMAN KT
Citation: Sm. Hutchins et Kt. Chapman, SOLID-PHASE SYNTHESIS OF TETRAHYDROISOQUINOLINES AND TETRAHYDROIMIDAZOPYRIDINES, Tetrahedron letters, 37(28), 1996, pp. 4865-4868
FISCHER INDOLE SYNTHESIS ON A SOLID SUPPORT
Authors: HUTCHINS SM CHAPMAN KT
Citation: Sm. Hutchins et Kt. Chapman, FISCHER INDOLE SYNTHESIS ON A SOLID SUPPORT, Tetrahedron letters, 37(28), 1996, pp. 4869-4872
DENDRIMER-SUPPORTED COMBINATORIAL CHEMISTRY
Authors: KIM RM MANNA M HUTCHINS SM GRIFFIN PR YATES NA BERNICK AM CHAPMAN KT
Citation: Rm. Kim et al., DENDRIMER-SUPPORTED COMBINATORIAL CHEMISTRY, Proceedings of the National Academy of Sciences of the United Statesof America, 93(19), 1996, pp. 10012-10017
A SYNTHETIC INHIBITOR OF INTERLEUKIN-1-BETA CONVERTING-ENZYME PREVENTS ENDOTOXIN-INDUCED INTERLEUKIN-1-BETA PRODUCTION IN-VITRO AND IN-VIVO
Authors: FLETCHER DS AGARWAL L CHAPMAN KT CHIN J EGGER LA LIMJUCO G LUELL S MACINTYRE DE PETERSON EP THORNBERRY NA KOSTURA MJ
Citation: Ds. Fletcher et al., A SYNTHETIC INHIBITOR OF INTERLEUKIN-1-BETA CONVERTING-ENZYME PREVENTS ENDOTOXIN-INDUCED INTERLEUKIN-1-BETA PRODUCTION IN-VITRO AND IN-VIVO, Journal of interferon & cytokine research, 15(3), 1995, pp. 243-248
INHIBITION OF MATRIX METALLOPROTEINASES BY N-CARBOXYALKYL DIPEPTIDES - ENHANCED POTENCY AND SELECTIVITY WITH SUBSTITUTED P-1' HOMOPHENYLALANINES
Authors: SAHOO SP CALDWELL CG CHAPMAN KT DURETTE PL ESSER CK KOPKA IE POLO SA SPEROW KM NIEDZWIECKI LM IZQUIERDOMARTIN M CHANG BC HARRISON RK STEIN RL MACCOSS M HAGMANN WK
Citation: Sp. Sahoo et al., INHIBITION OF MATRIX METALLOPROTEINASES BY N-CARBOXYALKYL DIPEPTIDES - ENHANCED POTENCY AND SELECTIVITY WITH SUBSTITUTED P-1' HOMOPHENYLALANINES, Bioorganic & medicinal chemistry letters, 5(20), 1995, pp. 2441-2446
INHIBITION OF INTERLEUKIN-1-BETA CONVERTING-ENZYME BY N-ACYL-ASPARTICACID KETONES
Authors: MJALLI AMM CHAPMAN KT ZHAO JJ THORNBERRY NA PETERSON EP MACCOSS M
Citation: Amm. Mjalli et al., INHIBITION OF INTERLEUKIN-1-BETA CONVERTING-ENZYME BY N-ACYL-ASPARTICACID KETONES, Bioorganic & medicinal chemistry letters, 5(13), 1995, pp. 1405-1408
INHIBITION OF INTERLEUKIN-1-BETA CONVERTING-ENZYME BY N-ACYL-ASPARTYLARYLOXYMETHYL KETONES
Authors: MJALLI AMM ZHAO JJ CHAPMAN KT THORNBERRY NA PETERSON EP MACCOSS M HAGMANN WK
Citation: Amm. Mjalli et al., INHIBITION OF INTERLEUKIN-1-BETA CONVERTING-ENZYME BY N-ACYL-ASPARTYLARYLOXYMETHYL KETONES, Bioorganic & medicinal chemistry letters, 5(13), 1995, pp. 1409-1414
SOLID-PHASE SYNTHESIS OF ARYL ETHERS VIA THE MITSUNOBU REACTION
Authors: RANO TA CHAPMAN KT
Citation: Ta. Rano et Kt. Chapman, SOLID-PHASE SYNTHESIS OF ARYL ETHERS VIA THE MITSUNOBU REACTION, Tetrahedron letters, 36(22), 1995, pp. 3789-3792
A STRATEGY FOR UREA LINKED DIAMINE LIBRARIES
Authors: HUTCHINS SM CHAPMAN KT
Citation: Sm. Hutchins et Kt. Chapman, A STRATEGY FOR UREA LINKED DIAMINE LIBRARIES, Tetrahedron letters, 36(15), 1995, pp. 2583-2586
MAGNETICALLY MANIPULATABLE POLYMERIC SUPPORTS FOR SOLID-PHASE ORGANIC-SYNTHESIS
Authors: SZYMONIFKA MJ CHAPMAN KT
Citation: Mj. Szymonifka et Kt. Chapman, MAGNETICALLY MANIPULATABLE POLYMERIC SUPPORTS FOR SOLID-PHASE ORGANIC-SYNTHESIS, Tetrahedron letters, 36(10), 1995, pp. 1597-1600
ACTIVATED KETONES AS POTENT REVERSIBLE INHIBITORS OF INTERLEUKIN-1-BETA CONVERTING-ENZYME
Authors: MJALLI AMM CHAPMAN KT MACCOSS M THORNBERRY NA PETERSON EP
Citation: Amm. Mjalli et al., ACTIVATED KETONES AS POTENT REVERSIBLE INHIBITORS OF INTERLEUKIN-1-BETA CONVERTING-ENZYME, Bioorganic & medicinal chemistry letters, 4(16), 1994, pp. 1965-1968
A GENERAL-METHOD FOR THE SOLID-PHASE SYNTHESIS OF UREAS
Authors: HUTCHINS SM CHAPMAN KT
Citation: Sm. Hutchins et Kt. Chapman, A GENERAL-METHOD FOR THE SOLID-PHASE SYNTHESIS OF UREAS, Tetrahedron letters, 35(24), 1994, pp. 4055-4058
STUDIES ON THE KINETIC AND CHEMICAL MECHANISM OF INHIBITION OF STROMELYSIN BY AN N-(CARBOXYALKYL)DIPEPTIDE
Authors: IZQUIERDOMARTIN M CHAPMAN KT HAGMANN WK STEIN RL
Citation: M. Izquierdomartin et al., STUDIES ON THE KINETIC AND CHEMICAL MECHANISM OF INHIBITION OF STROMELYSIN BY AN N-(CARBOXYALKYL)DIPEPTIDE, Biochemistry, 33(6), 1994, pp. 1356-1365
Risultati: 1-25 | 26-30