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Results: 26-50/130
ANTIVIRAL ACTIVITIES OF BETA-ENANTIOMERS OF 3'-SUBSTITUTED-3'-DEOXYTHYMIDINE ANALOGS
Authors: FARAJ A ELALAOUI MA PAVIA G GOSSELIN G IMBACH JL SCHINAZI RF SOMMADOSSI JP
Citation: A. Faraj et al., ANTIVIRAL ACTIVITIES OF BETA-ENANTIOMERS OF 3'-SUBSTITUTED-3'-DEOXYTHYMIDINE ANALOGS, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1287-1290
THE PRONUCLEOTIDE APPROACH .1. SYNTHESIS, ANTI-HIV ACTIVITY AND PRELIMINARY STABILITY STUDIES OF MONONUCLEOSIDE S,S'-BIS(O-ACYL-2-OXYETHYL)PHOSPHORODITHIOLATES
Authors: SCHLIENGER N PERIGAUD C GOSSELIN G LEFEBVRE I POMPON A AUBERTIN AM KIRN A IMBACH JL
Citation: N. Schlienger et al., THE PRONUCLEOTIDE APPROACH .1. SYNTHESIS, ANTI-HIV ACTIVITY AND PRELIMINARY STABILITY STUDIES OF MONONUCLEOSIDE S,S'-BIS(O-ACYL-2-OXYETHYL)PHOSPHORODITHIOLATES, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1321-1324
THE PRONUCLEOTIDE APPROACH .2. SYNTHESIS AND PRELIMINARY STABILITY STUDIES OF MONONUCLEOSIDE GLYCOSYL PHOSPHOTRIESTER DERIVATIVES
Authors: SCHLIENGER N PERIGAUD C GOSSELIN G IMBACH JL
Citation: N. Schlienger et al., THE PRONUCLEOTIDE APPROACH .2. SYNTHESIS AND PRELIMINARY STABILITY STUDIES OF MONONUCLEOSIDE GLYCOSYL PHOSPHOTRIESTER DERIVATIVES, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1325-1329
THE PRONUCLEOTIDE APPROACH .3. SYNTHESIS, ANTI-HBV ACTIVITY AND STABILITY STUDIES OF THE BIS(S-PIVALOYL-2-THIOETHYL) PHOSPHOTRIESTER DERIVATIVE OF ACYCLOVIR
Authors: VALETTE G GIRARDET JL POMPON A PERIGAUD C GOSSELIN G KORBA B HANTZ O IMBACH JL
Citation: G. Valette et al., THE PRONUCLEOTIDE APPROACH .3. SYNTHESIS, ANTI-HBV ACTIVITY AND STABILITY STUDIES OF THE BIS(S-PIVALOYL-2-THIOETHYL) PHOSPHOTRIESTER DERIVATIVE OF ACYCLOVIR, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1331-1335
NEW UNNATURAL L-NUCLEOSIDE ENANTIOMERS - FROM THEIR STEREOSPECIFIC SYNTHESIS TO THEIR BIOLOGICAL-ACTIVITIES
Authors: GOSSELIN G BOUDOU V GRIFFON JF PAVIA G PIERRA C IMBACH JL AUBERTIN AM SCHINAZI RF FARAJ A SOMMADOSSI JP
Citation: G. Gosselin et al., NEW UNNATURAL L-NUCLEOSIDE ENANTIOMERS - FROM THEIR STEREOSPECIFIC SYNTHESIS TO THEIR BIOLOGICAL-ACTIVITIES, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1389-1398
REPLACEMENT OF THE PHOSPHODIESTER BACKBONE OF OLIGODEOXYNUCLEOTIDE ANALOGS BY NONIONIC PHOSPHORAMIDATE (P-NH2)
Authors: PEYROTTES S VASSEUR JJ IMBACH JL RAYNER B
Citation: S. Peyrottes et al., REPLACEMENT OF THE PHOSPHODIESTER BACKBONE OF OLIGODEOXYNUCLEOTIDE ANALOGS BY NONIONIC PHOSPHORAMIDATE (P-NH2), Nucleosides & nucleotides, 16(7-9), 1997, pp. 1551-1554
CONVENIENT METHOD FOR LABELING OLIGONUCLEOTIDE ANALOGS BY A FLUOROGENIC TAG FOR DIRECT IN-VITRO AND IN-VIVO VISUALIZATION OF CARBOXYESTERASE ACTIVITY
Authors: LAURENT A DEBARTVASSEUR F IMBACH JL RAYNER B
Citation: A. Laurent et al., CONVENIENT METHOD FOR LABELING OLIGONUCLEOTIDE ANALOGS BY A FLUOROGENIC TAG FOR DIRECT IN-VITRO AND IN-VIVO VISUALIZATION OF CARBOXYESTERASE ACTIVITY, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1765-1766
STUDY OF THE ENANTIOSELECTIVITY OF ENZYMES INVOLVED IN NUCLEOSIDE ANALOG METABOLISM - DEOXYCYTIDINE KINASE
Authors: SHAFIEE M BOUDOU V GRIFFON JF POMPON A GOSSELIN G ERIKSSON S IMBACH JL MAURY G
Citation: M. Shafiee et al., STUDY OF THE ENANTIOSELECTIVITY OF ENZYMES INVOLVED IN NUCLEOSIDE ANALOG METABOLISM - DEOXYCYTIDINE KINASE, Nucleosides & nucleotides, 16(7-9), 1997, pp. 1767-1770
PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF BASE-SENSITIVE OLIGONUCLEOTIDES
Authors: DELLAQUILA C IMBACH JL RAYNER B
Citation: C. Dellaquila et al., PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF BASE-SENSITIVE OLIGONUCLEOTIDES, Tetrahedron letters, 38(30), 1997, pp. 5289-5292
EFFECT OF THE ALKYL CHAIN-LENGTH ON THE ANTI-HIV EFFICIENCY OF PRONUCLEOTIDES BEARING S-ACYL-THIOALKYL PHOSPHATE PROTECTING GROUPS
Authors: EGRON D PERIGAUD C GOSSELIN G AUBERTIN AM IMBACH JL
Citation: D. Egron et al., EFFECT OF THE ALKYL CHAIN-LENGTH ON THE ANTI-HIV EFFICIENCY OF PRONUCLEOTIDES BEARING S-ACYL-THIOALKYL PHOSPHATE PROTECTING GROUPS, Bulletin des Societes chimiques belges, 106(7-8), 1997, pp. 461-466
SOLID-LIQUID PHASE-TRANSFER CATALYSIS .3. SYNTHESIS OF AZIDO ACYCLIC NUCLEOSIDES OF PYRIMIDINE
Authors: LAZREK HB TAOURIRTE M BARASCUT JL IMBACH JL
Citation: Hb. Lazrek et al., SOLID-LIQUID PHASE-TRANSFER CATALYSIS .3. SYNTHESIS OF AZIDO ACYCLIC NUCLEOSIDES OF PYRIMIDINE, Bulletin des Societes chimiques belges, 106(1), 1997, pp. 19-24
LACK OF ENANTIOSPECIFICITY OF HUMAN 2'-DEOXYCYTIDINE KINASE - RELEVANCE FOR THE ACTIVATION OF BETA-L-DEOXYCYTIDINE ANALOGS AS ANTINEOPLASTIC AND ANTIVIRAL AGENTS
Authors: VERRI A FOCHER F PRIORI G GOSSELIN G IMBACH JL CAPOBIANCO M GARBESI A SPADARI S
Citation: A. Verri et al., LACK OF ENANTIOSPECIFICITY OF HUMAN 2'-DEOXYCYTIDINE KINASE - RELEVANCE FOR THE ACTIVATION OF BETA-L-DEOXYCYTIDINE ANALOGS AS ANTINEOPLASTIC AND ANTIVIRAL AGENTS, Molecular pharmacology, 51(1), 1997, pp. 132-138
SYNTHESIS AND STUDIES OF MONONUCLEOSIDE GLYCOSYL PHOSPHOTRIESTER DERIVATIVES
Authors: SCHLIENGER N PERIGAUD C GOSSELIN G IMBACH JL
Citation: N. Schlienger et al., SYNTHESIS AND STUDIES OF MONONUCLEOSIDE GLYCOSYL PHOSPHOTRIESTER DERIVATIVES, Journal of organic chemistry, 62(21), 1997, pp. 7216-7221
NOVEL 3'-C N-SUBSTITUTED 2',3'-BETA-D-DIDEOXYNUCLEOSIDES AS POTENTIALCHEMOTHERAPEUTIC-AGENTS .1. THYMIDINE DERIVATIVES - SYNTHESIS, STRUCTURE, AND BROAD-SPECTRUM ANTIVIRAL PROPERTIES/
Authors: FEDOROV II KAZMINA EM GURSKAYA GV JASKO MV ZAVODNIC VE BALZARINI J DECLERCQ E FARAJ A SOMMADOSSI JP IMBACH JL GOSSELIN G
Citation: Ii. Fedorov et al., NOVEL 3'-C N-SUBSTITUTED 2',3'-BETA-D-DIDEOXYNUCLEOSIDES AS POTENTIALCHEMOTHERAPEUTIC-AGENTS .1. THYMIDINE DERIVATIVES - SYNTHESIS, STRUCTURE, AND BROAD-SPECTRUM ANTIVIRAL PROPERTIES/, Journal of medicinal chemistry, 40(4), 1997, pp. 486-494
ENZYMATIC-PROPERTIES OF THE UNNATURAL BETA-L-ENANTIOMERS OF 2',3'-DIDEOXYADENOSINE AND 2',3'-DIDEHYDRO-2',3'-DIDEOXYADENOSINE
Authors: PELICANO H PIERRA C ERIKSSON S GOSSELIN G IMBACH JL MAURY G
Citation: H. Pelicano et al., ENZYMATIC-PROPERTIES OF THE UNNATURAL BETA-L-ENANTIOMERS OF 2',3'-DIDEOXYADENOSINE AND 2',3'-DIDEHYDRO-2',3'-DIDEOXYADENOSINE, Journal of medicinal chemistry, 40(24), 1997, pp. 3969-3973
STEREOISOMERS OF DEOXYNUCLEOSIDE 5'-TRIPHOSPHATES AS SUBSTRATES FOR TEMPLATE-DEPENDENT AND TEMPLATE-INDEPENDENT DNA-POLYMERASES
Authors: SEMIZAROV DG ARZUMANOV AA DYATKINA NB MEYER A VICHIERGUERRE S GOSSELIN G RAYNER B IMBACH JL KRAYEVSKY AA
Citation: Dg. Semizarov et al., STEREOISOMERS OF DEOXYNUCLEOSIDE 5'-TRIPHOSPHATES AS SUBSTRATES FOR TEMPLATE-DEPENDENT AND TEMPLATE-INDEPENDENT DNA-POLYMERASES, The Journal of biological chemistry, 272(14), 1997, pp. 9556-9560
STUDY OF THE SUBSTRATE-BINDING PROPERTIES OF BOVINE LIVER ADENOSINE KINASE AND INHIBITION BY FLUORESCENT NUCLEOSIDE ANALOGS
Authors: PELICANO H MAURY G ELALAOUI A SHAFIEE M IMBACH JL GOODY RS DIVITA G
Citation: H. Pelicano et al., STUDY OF THE SUBSTRATE-BINDING PROPERTIES OF BOVINE LIVER ADENOSINE KINASE AND INHIBITION BY FLUORESCENT NUCLEOSIDE ANALOGS, European journal of biochemistry, 248(3), 1997, pp. 930-937
SYNTHESIS AND EVALUATION OF GLUCURONIC-ACID DERIVATIVES AS ALKYLATING-AGENTS FOR THE REVERSIBLE MASKING OF INTERNUCLEOSIDE GROUPS OF ANTISENSE OLIGONUCLEOTIDES
Authors: MIGNET N CHAIX C RAYNER B IMBACH JL
Citation: N. Mignet et al., SYNTHESIS AND EVALUATION OF GLUCURONIC-ACID DERIVATIVES AS ALKYLATING-AGENTS FOR THE REVERSIBLE MASKING OF INTERNUCLEOSIDE GROUPS OF ANTISENSE OLIGONUCLEOTIDES, Carbohydrate research, 303(1), 1997, pp. 17-24
EFFECT OF STEREOISOMERISM ON THE CELLULAR PHARMACOLOGY OF BETA-ENANTIOMERS OF CYTIDINE ANALOGS IN HEP-G2 CELLS
Authors: MARTIN LT FARAJ A SCHINAZI RF GOSSELIN G MATHE C IMBACH JL SOMMADOSSI JP
Citation: Lt. Martin et al., EFFECT OF STEREOISOMERISM ON THE CELLULAR PHARMACOLOGY OF BETA-ENANTIOMERS OF CYTIDINE ANALOGS IN HEP-G2 CELLS, Biochemical pharmacology, 53(1), 1997, pp. 75-87
EFFECT OF 5-METHYLCYTOSINE AND 5-BROMOURACIL IN ALPHA-OLIGODEOXYRIBONUCLEOTIDES ON THE STABILITY OF ALPHA-BETA-BETA TRIPLE HELICES
Authors: MORVAN F CHAIX C RAYNER B IMBACH JL
Citation: F. Morvan et al., EFFECT OF 5-METHYLCYTOSINE AND 5-BROMOURACIL IN ALPHA-OLIGODEOXYRIBONUCLEOTIDES ON THE STABILITY OF ALPHA-BETA-BETA TRIPLE HELICES, New journal of chemistry, 20(5), 1996, pp. 589-593
THE PROOLIGONUCLEOTIDE APPROACH .3. SYNTHESIS AND BIOREVERSIBILITY OFA CHIMERIC PHOSPHORODITHIOATE PROOLIGONUCLEOTIDE
Authors: TOSQUELLAS G BARBER I MORVAN F RAYNER B IMBACH JL
Citation: G. Tosquellas et al., THE PROOLIGONUCLEOTIDE APPROACH .3. SYNTHESIS AND BIOREVERSIBILITY OFA CHIMERIC PHOSPHORODITHIOATE PROOLIGONUCLEOTIDE, Bioorganic & medicinal chemistry letters, 6(4), 1996, pp. 457-462
ANTI-HUMAN IMMUNODEFICIENCY AND ANTI-HEPATITIS-B VIRUS ACTIVITIES OF BETA-L-2',3'-DIDEOXY PURINE NUCLEOSIDES
Authors: BOLON PJ WANG PY CHU CK GOSSELIN G BOUDOU V PIERRA C MATHE C IMBACH JL FARAJ A ALAOUI MA SOMMADOSSI JP PAI SB ZHU YL LIN JS CHENG YC SCHINAZI RF
Citation: Pj. Bolon et al., ANTI-HUMAN IMMUNODEFICIENCY AND ANTI-HEPATITIS-B VIRUS ACTIVITIES OF BETA-L-2',3'-DIDEOXY PURINE NUCLEOSIDES, Bioorganic & medicinal chemistry letters, 6(14), 1996, pp. 1657-1662
COMPARISON OF CYTOTOXICITY OF MONONUCLEOSIDE PHOSPHOTRIESTER DERIVATIVES BEARING BIOLABILE PHOSPHATE PROTECTING GROUPS IN NORMAL HUMAN BONE-MARROW PROGENITOR CELLS
Authors: PERIGAUD C GIRARDET JL LEFEBVRE I XIE MY AUBERTIN AM KIRN A GOSSELIN G IMBACH JL SOMMADOSSI JP
Citation: C. Perigaud et al., COMPARISON OF CYTOTOXICITY OF MONONUCLEOSIDE PHOSPHOTRIESTER DERIVATIVES BEARING BIOLABILE PHOSPHATE PROTECTING GROUPS IN NORMAL HUMAN BONE-MARROW PROGENITOR CELLS, Antiviral chemistry & chemotherapy, 7(6), 1996, pp. 338-345
INHIBITION OF HEPATITIS-B VIRUS-REPLICATION BY NUCLEOSIDE ENANTIOMERSOF BETA-2',3'-DIDEOXYPURINE ANALOGS
Authors: ELALAOUI AM FARAJ A PIERRA C BOUDOU V JOHNSON R MATHE C GOSSELIN G KORBA BE IMBACH JL SCHINAZI RF SOMMADOSSI JP
Citation: Am. Elalaoui et al., INHIBITION OF HEPATITIS-B VIRUS-REPLICATION BY NUCLEOSIDE ENANTIOMERSOF BETA-2',3'-DIDEOXYPURINE ANALOGS, Antiviral chemistry & chemotherapy, 7(5), 1996, pp. 276-280
ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ACTIVITIES OF DIDEOXYNUCLEOSIDE PHOSPHOTRIESTER DERIVATIVES IN PRIMARY MONOCYTES MACROPHAGES
Authors: THUMANNSCHWEITZER C GOSSELIN G PERIGAUD C BENZARIA S GIRARDET JL LEFEBVRE I IMBACH JL KIRN A AUBERTIN AM
Citation: C. Thumannschweitzer et al., ANTI-HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 ACTIVITIES OF DIDEOXYNUCLEOSIDE PHOSPHOTRIESTER DERIVATIVES IN PRIMARY MONOCYTES MACROPHAGES, Research in virology, 147(2-3), 1996, pp. 155-163
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