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Results: 1-12 |
Results: 12
Lewis-acid catalysed arylation of the hydroxyamino sugar moiety of the natural product SB-219383
Authors: Berge, JM Houge-Frydrych, CSV Jarvest, RL
Citation: Jm. Berge et al., Lewis-acid catalysed arylation of the hydroxyamino sugar moiety of the natural product SB-219383, J CHEM S P1, (20), 2001, pp. 2521-2523
Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors
Authors: Qiu, XY Janson, CA Smith, WW Green, SM McDevitt, P Johanson, K Carter, P Hibbs, M Lewis, C Chalker, A Fosberry, A Lalonde, J Berge, J Brown, P Houge-Frydrych, CSV Jarvest, RL
Citation: Xy. Qiu et al., Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors, PROTEIN SCI, 10(10), 2001, pp. 2008-2016
Synthetic analogues of SB-219383. Novel C-glycosyl peptides as inhibitors of tyrosyl tRNA synthetase
Authors: Brown, P Eggleston, DS Haltiwanger, RC Jarvest, RL Mensah, L O'Hanlon, PJ Pope, AJ
Citation: P. Brown et al., Synthetic analogues of SB-219383. Novel C-glycosyl peptides as inhibitors of tyrosyl tRNA synthetase, BIOORG MED, 11(5), 2001, pp. 711-714
Potent synthetic inhibitors of tyrosyl tRNA synthetase derived from C-pyranosyl analogues of SB-219383
Authors: Jarvest, RL Berge, JM Brown, P Hamprecht, DW McNair, DJ Mensah, L O'Hanlon, PJ Pope, AJ
Citation: Rl. Jarvest et al., Potent synthetic inhibitors of tyrosyl tRNA synthetase derived from C-pyranosyl analogues of SB-219383, BIOORG MED, 11(5), 2001, pp. 715-718
Inhibitors of bacterial tyrosyl tRNA synthetase: Synthesis of carbocyclic analogues of the natural product SB-219383
Authors: Jarvest, RL Berge, JM Houge-Frydrych, CSV Mensah, LM O'Hanlon, PJ Pope, AJ
Citation: Rl. Jarvest et al., Inhibitors of bacterial tyrosyl tRNA synthetase: Synthesis of carbocyclic analogues of the natural product SB-219383, BIOORG MED, 11(18), 2001, pp. 2499-2502
Inhibitors of bacterial tyrosyl tRNA synthetase: Synthesis of four stereoisomeric analogues of the natural product SB-219383
Authors: Berge, JM Copley, RCB Eggleston, DS Hamprecht, DW Jarvest, RL Mensah, LM O'Hanlon, PJ Pope, AJ
Citation: Jm. Berge et al., Inhibitors of bacterial tyrosyl tRNA synthetase: Synthesis of four stereoisomeric analogues of the natural product SB-219383, BIOORG MED, 10(16), 2000, pp. 1811-1814
Aminoalkyl adenylate and aminoacyl sulfamate intermediate analogues differing greatly in affinity for their cognate Staphylococcus aureus aminoacyl tRNA synthetases
Authors: Forrest, AK Jarvest, RL Mensah, LM O'Hanlon, PJ Pope, AJ Sheppard, RJ
Citation: Ak. Forrest et al., Aminoalkyl adenylate and aminoacyl sulfamate intermediate analogues differing greatly in affinity for their cognate Staphylococcus aureus aminoacyl tRNA synthetases, BIOORG MED, 10(16), 2000, pp. 1871-1874
The synthesis of 5-alkoxy and 5-amino substituted thiophenes
Authors: Pinto, IL Jarvest, RL Serafinowska, HT
Citation: Il. Pinto et al., The synthesis of 5-alkoxy and 5-amino substituted thiophenes, TETRAHEDR L, 41(10), 2000, pp. 1597-1600
Synthesis and activity of analogues of SB-219383: Novel potent inhibitors of bacterial tyrosyl tRNA synthetase
Authors: Berge, JM Broom, NJP Houge-Frydrych, CSV Jarvest, RL Mensah, L McNair, DJ O'Hanlon, PJ Pope, AJ Rittenhouse, S
Citation: Jm. Berge et al., Synthesis and activity of analogues of SB-219383: Novel potent inhibitors of bacterial tyrosyl tRNA synthetase, J ANTIBIOT, 53(11), 2000, pp. 1282-1292
Inhibition of herpes proteases and antiviral activity of 2-substituted thieno[2,3-d]oxazinones
Authors: Jarvest, RL Pinto, IL Ashman, SM Dabrowski, CE Fernandez, AV Jennings, LJ Lavery, P Tew, DG
Citation: Rl. Jarvest et al., Inhibition of herpes proteases and antiviral activity of 2-substituted thieno[2,3-d]oxazinones, BIOORG MED, 9(3), 1999, pp. 443-448
Inhibition of human cytomegalovirus protease by enedione derivatives of thieno[2,3-d]oxazinones through a novel dual acylation/alkylation mechanism
Authors: Pinto, IL Jarvest, RL Clarke, B Dabrowski, CE Fenwick, A Gorczyca, MM Jennings, LJ Lavery, P Sternberg, EJ Tew, DG West, A
Citation: Il. Pinto et al., Inhibition of human cytomegalovirus protease by enedione derivatives of thieno[2,3-d]oxazinones through a novel dual acylation/alkylation mechanism, BIOORG MED, 9(3), 1999, pp. 449-452
Interaction of tyrosyl aryl dipeptides with S-aureus tyrosyl tRNA synthetase: Inhibition and crystal structure of a complex
Authors: Jarvest, RL Berge, JM Houge-Frydrych, CSV Janson, C Mensah, LM O'Hanlon, PJ Pope, A Saldanha, A Qiu, XY
Citation: Rl. Jarvest et al., Interaction of tyrosyl aryl dipeptides with S-aureus tyrosyl tRNA synthetase: Inhibition and crystal structure of a complex, BIOORG MED, 9(19), 1999, pp. 2859-2862
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