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Results: 1-25 |
Results: 25
Design of new mononucleotide prodrugs: Aryl (SATE) phosphotriester derivatives
Authors: Peyrottes, S Schlienger, N Beltran, T Lefebvre, I Pompon, A Gosselin, G Aubertin, AM Imbach, JL Perigaud, C
Citation: S. Peyrottes et al., Design of new mononucleotide prodrugs: Aryl (SATE) phosphotriester derivatives, NUCLEOS NUC, 20(4-7), 2001, pp. 315-321
Synthesis and study of a new series of phosphoramidate derivatives as mononucleotide prodrugs
Authors: Egron, D Perigaud, C Gosselin, G Aubertin, AM Imbach, JL
Citation: D. Egron et al., Synthesis and study of a new series of phosphoramidate derivatives as mononucleotide prodrugs, NUCLEOS NUC, 20(4-7), 2001, pp. 751-754
Rational design of a new series of pronucleotide
Authors: Beltran, T Egron, D Pompon, A Lefebvre, I Perigaud, C Gosselin, G Aubertin, AM Imbach, JL
Citation: T. Beltran et al., Rational design of a new series of pronucleotide, BIOORG MED, 11(13), 2001, pp. 1775-1777
New bis(SATE) prodrug of AZT 5 '-monophosphate: In vitro anti-HIV activity, stability, and potential oral absorption
Authors: Shafiee, M Deferme, S Villard, AL Egron, D Gosselin, G Imbach, JL Lioux, T Pompon, A Varray, S Aubertin, AM Van den Mooter, G Kinget, R Perigaud, C Augustijns, P
Citation: M. Shafiee et al., New bis(SATE) prodrug of AZT 5 '-monophosphate: In vitro anti-HIV activity, stability, and potential oral absorption, J PHARM SCI, 90(4), 2001, pp. 448-463
Inhibition of the Ras-dependent mitogenic pathway by phosphopeptide prodrugs with antiproliferative properties
Authors: Liu, WQ Vidal, M Mathe, C Perigaud, C Garbay, C
Citation: Wq. Liu et al., Inhibition of the Ras-dependent mitogenic pathway by phosphopeptide prodrugs with antiproliferative properties, BIOORG MED, 10(7), 2000, pp. 669-672
Pharmacokinetics of bis(t-butyl-SATE)-AZTMP, a bispivaloylthioethyl prodrug for intracellular delivery of zidovudine monophosphate, in mice
Authors: Tan, XL Boudinot, FD Chu, CK Egron, D Perigaud, C Gosselin, G Imbach, JL
Citation: Xl. Tan et al., Pharmacokinetics of bis(t-butyl-SATE)-AZTMP, a bispivaloylthioethyl prodrug for intracellular delivery of zidovudine monophosphate, in mice, ANTIVIR CHE, 11(3), 2000, pp. 203-211
ENSO simulated by intermediate coupled models and evaluated with observations over 1970-98. Part I: Role of the off-equatorial variability
Authors: Perigaud, C Melin, F Cassou, C
Citation: C. Perigaud et al., ENSO simulated by intermediate coupled models and evaluated with observations over 1970-98. Part I: Role of the off-equatorial variability, J CLIMATE, 13(10), 2000, pp. 1605-1634
ENSO simulated by intermediate coupled models and evaluated with observations over 1970-98. Part II: Role of the off-equatorial ocean and meridional winds
Authors: Cassou, C Perigaud, C
Citation: C. Cassou et C. Perigaud, ENSO simulated by intermediate coupled models and evaluated with observations over 1970-98. Part II: Role of the off-equatorial ocean and meridional winds, J CLIMATE, 13(10), 2000, pp. 1635-1663
S-acyl-2-thioethyl aryl phosphotriester derivatives as mononucleotide prodrugs
Authors: Schlienger, N Peyrottes, S Kassem, T Imbach, JL Gosselin, G Aubertin, AM Perigaud, C
Citation: N. Schlienger et al., S-acyl-2-thioethyl aryl phosphotriester derivatives as mononucleotide prodrugs, J MED CHEM, 43(23), 2000, pp. 4570-4574
ddC- and 3TC-bis(SATE) monophosphate prodrugs overcome cellular resistancemechanisms to HIV-1 associated with cytidine kinase deficiency
Authors: Groschel, B Himmel, N Cinatl, J Perigaud, C Gosselin, G Imbach, JL Doerr, HW Cinatl, J
Citation: B. Groschel et al., ddC- and 3TC-bis(SATE) monophosphate prodrugs overcome cellular resistancemechanisms to HIV-1 associated with cytidine kinase deficiency, NUCLEOS NUC, 18(4-5), 1999, pp. 921-926
Prodrugs of Ara-CMP and Ara-AMP with a S-acyl-2-thioethyl (SATE) biolabilephosphate protecting group: Synthesis and biological evaluation
Authors: Bazzanini, R Manfredini, S Durini, E Groschel, B Cinatl, J Balzarini, J De Clercq, E Imbach, JL Perigaud, C Gosselin, G
Citation: R. Bazzanini et al., Prodrugs of Ara-CMP and Ara-AMP with a S-acyl-2-thioethyl (SATE) biolabilephosphate protecting group: Synthesis and biological evaluation, NUCLEOS NUC, 18(4-5), 1999, pp. 971-972
Anti-HIV pronucleotides: Sate versus phenyl as a protecting grow of AZT phosphoramidate derivatives
Authors: Beltran, T Egron, D Lefebvre, I Perigaud, C Pompon, A Gosselin, G Aubertin, AM Imbach, JL
Citation: T. Beltran et al., Anti-HIV pronucleotides: Sate versus phenyl as a protecting grow of AZT phosphoramidate derivatives, NUCLEOS NUC, 18(4-5), 1999, pp. 973-975
Synthesis and anti-HIV activity of some S-acyl-2-thioethyl (SATE) phosphoramidate derivatives of 3 '-azido-2 ',3 '-dideoxythymidine
Authors: Egron, D Perigaud, C Gosselin, G Aubertin, AM Imbach, JL
Citation: D. Egron et al., Synthesis and anti-HIV activity of some S-acyl-2-thioethyl (SATE) phosphoramidate derivatives of 3 '-azido-2 ',3 '-dideoxythymidine, NUCLEOS NUC, 18(4-5), 1999, pp. 981-982
Synthesis, anti-HIV activity and stability studies of 3 '-azido-2 ',3 '-dideoxythymidine 5 '-fluorophosphate
Authors: Egron, D Arzumanov, AA Dyatkina, NB Krayevsky, A Imbach, JL Aubertin, AM Gosselin, G Perigaud, C
Citation: D. Egron et al., Synthesis, anti-HIV activity and stability studies of 3 '-azido-2 ',3 '-dideoxythymidine 5 '-fluorophosphate, NUCLEOS NUC, 18(4-5), 1999, pp. 983-984
Intracellular metabolism of beta-L-ddAMP-bis(tbutylSATE), a potent inhibitor of hepatitis B virus replication
Authors: Faraj, A Placidi, L Perigaud, C Cretton-Scott, E Gosselin, G Martin, LT Pierra, C Schinazi, RF Imbach, JL Sommadossi, JP
Citation: A. Faraj et al., Intracellular metabolism of beta-L-ddAMP-bis(tbutylSATE), a potent inhibitor of hepatitis B virus replication, NUCLEOS NUC, 18(4-5), 1999, pp. 987-988
Synthesis and in vitro antiviral activity of some symmetrical phosphoramidate dimers of AZT
Authors: Kers, I Girardet, JL Gosselin, G Perigaud, C Imbach, JL Stawinski, J
Citation: I. Kers et al., Synthesis and in vitro antiviral activity of some symmetrical phosphoramidate dimers of AZT, NUCLEOS NUC, 18(4-5), 1999, pp. 993-994
Synthesis of the tBuSATE pronucleotide of AZT by two different synthetic approaches
Authors: Lannuzel, M Egron, D Imbach, JL Gosselin, G Perigaud, C
Citation: M. Lannuzel et al., Synthesis of the tBuSATE pronucleotide of AZT by two different synthetic approaches, NUCLEOS NUC, 18(4-5), 1999, pp. 1001-1002
Synthesis of new PMEA diphosphate mimics
Authors: Laux, WHG Perigaud, C Imbach, JL Gosselin, G
Citation: Whg. Laux et al., Synthesis of new PMEA diphosphate mimics, NUCLEOS NUC, 18(4-5), 1999, pp. 1003-1004
New series of mixed pronucleotides. Synthesis and anti-HIV activities of mononucleoside phenyl SATE phosphotriesters
Authors: Schlienger, N Peyrottes, S Aubertin, AM Gosselin, G Imbach, JL Perigaud, C
Citation: N. Schlienger et al., New series of mixed pronucleotides. Synthesis and anti-HIV activities of mononucleoside phenyl SATE phosphotriesters, NUCLEOS NUC, 18(4-5), 1999, pp. 1025-1026
Synthesis and anti-retroviral activity of O,O '-bis(3 '-azido-2 ',3 '-dideoxythymidin-5 '-yl) phosphoramidate derivatives
Authors: Kers, I Stawinski, J Girardet, JL Imbach, JL Perigaud, C Gosselin, G Aubertin, AM
Citation: I. Kers et al., Synthesis and anti-retroviral activity of O,O '-bis(3 '-azido-2 ',3 '-dideoxythymidin-5 '-yl) phosphoramidate derivatives, NUCLEOS NUC, 18(10), 1999, pp. 2317-2325
The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir - Part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir
Authors: Perigaud, C Gosselin, G Girardet, JL Korba, BE Imbach, JL
Citation: C. Perigaud et al., The S-acyl-2-thioethyl pronucleotide approach applied to acyclovir - Part I. Synthesis and in vitro anti-hepatitis B virus activity of bis(S-acyl-2-thioethyl)phosphotriester derivatives of acyclovir, ANTIVIR RES, 40(3), 1999, pp. 167-178
The SATE pronucleotide approach applied to acyclovir - Part II. Effects ofbis(SATE)phosphotriester derivatives of acyclovir on duck hepatitis B virus replication in vitro and in vivo
Authors: Hantz, O Perigaud, C Borel, C Jamard, C Zoulim, F Trepo, C Imbach, JL Gosselin, G
Citation: O. Hantz et al., The SATE pronucleotide approach applied to acyclovir - Part II. Effects ofbis(SATE)phosphotriester derivatives of acyclovir on duck hepatitis B virus replication in vitro and in vivo, ANTIVIR RES, 40(3), 1999, pp. 179-187
Inhibition of adenylyl cyclase by acyclic nucleoside phosphonate antiviralagents
Authors: Shoshani, I Laux, WHG Perigaud, C Gosselin, G Johnson, RA
Citation: I. Shoshani et al., Inhibition of adenylyl cyclase by acyclic nucleoside phosphonate antiviralagents, J BIOL CHEM, 274(49), 1999, pp. 34742-34744
2-(glucosylthio)ethyl groups as potential biolabile phosphate-protecting groups of mononucleotides
Authors: Schlienger, N Perigaud, C Aubertin, AM Thumann, C Gosselin, G Imbach, JL
Citation: N. Schlienger et al., 2-(glucosylthio)ethyl groups as potential biolabile phosphate-protecting groups of mononucleotides, HELV CHIM A, 82(11), 1999, pp. 2044-2051
A rational strategy for the design of anti-hepatitis B virus nucleotide derivatives
Authors: Perigaud, C Gosselin, G Imbach, JL
Citation: C. Perigaud et al., A rational strategy for the design of anti-hepatitis B virus nucleotide derivatives, THERAPIES FOR VIRAL HEPATITIS, 1998, pp. 313-319
Risultati: 1-25 |