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Results: 1-25 | 26-50 | 51-72
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Stereochemical control of DNA biosynthesis
Authors: Sosunov, VV Santamaria, F Victorova, LS Gosselin, G Rayner, B Krayevsky, AA
Citation: Vv. Sosunov et al., Stereochemical control of DNA biosynthesis, NUCL ACID R, 28(5), 2000, pp. 1170-1175
Effects of beta-L-3 '-azido-3 '-deoxythymidine 5 '-triphosphate on host and viral DNA polymerases
Authors: Faraj, A El Alaoui, AM Gosselin, G Imbach, JL Morrow, C Sommadossi, JP
Citation: A. Faraj et al., Effects of beta-L-3 '-azido-3 '-deoxythymidine 5 '-triphosphate on host and viral DNA polymerases, ANTIVIR RES, 47(2), 2000, pp. 97-102
Synthesis and antiviral evaluation of some beta-L-2 ',3 '-dideoxy-5-chloropyrimidine nucleosides and pronucleotides
Authors: Pierra, C Imbach, JL De Clercq, E Balzarini, J Van Aerschot, A Herdewijn, P Faraj, A Loi, AG Sommadossi, JP Gosselin, G
Citation: C. Pierra et al., Synthesis and antiviral evaluation of some beta-L-2 ',3 '-dideoxy-5-chloropyrimidine nucleosides and pronucleotides, ANTIVIR RES, 45(3), 2000, pp. 169-183
Intracellular metabolism of beta-L-2 ',3 '-dideoxyadenosine: Relevance to its limited antiviral activity
Authors: Placidi, L Cretton-Scott, E Gosselin, G Pierra, C Schinazi, RF Imbach, JL El Kouni, M Sommadossi, JP
Citation: L. Placidi et al., Intracellular metabolism of beta-L-2 ',3 '-dideoxyadenosine: Relevance to its limited antiviral activity, ANTIM AG CH, 44(4), 2000, pp. 853-858
S-acyl-2-thioethyl aryl phosphotriester derivatives as mononucleotide prodrugs
Authors: Schlienger, N Peyrottes, S Kassem, T Imbach, JL Gosselin, G Aubertin, AM Perigaud, C
Citation: N. Schlienger et al., S-acyl-2-thioethyl aryl phosphotriester derivatives as mononucleotide prodrugs, J MED CHEM, 43(23), 2000, pp. 4570-4574
Randomized trial comparing intravenous nitroglycerin and heparin for treatment of unstable angina secondary to restenosis after coronary artery angioplasty
Authors: Doucet, S Malekianpour, M Theroux, P Bilodeau, L Cote, G de Guise, P Dupuis, J Joyal, M Gosselin, G Tanguay, JF Juneau, M Harel, F Nattel, S Tardif, JC Lesperance, J
Citation: S. Doucet et al., Randomized trial comparing intravenous nitroglycerin and heparin for treatment of unstable angina secondary to restenosis after coronary artery angioplasty, CIRCULATION, 101(9), 2000, pp. 955-961
Effects of metoprolol CR in patients with ischemic and dilated cardiomyopathy - The randomized evaluation of strategies for left ventricular dysfunction pilot study
Authors: Cirillo, W Decanini, R Coelho, OR Avezum, A Peixoto, MSP Piegas, LS Neto, JMR Paiva, M Carvalho, AC de Almeida, DR Fernandes, IML Malavasi, MC Pavanello, R Canesin, M Ishii, S Barretto, ACP Imrie, J Moore, R Woo, K Bernstein, V Mizgala, HF Mooney, S Hilbich, D Kuritzky, R Rupka, DW Blackwell, MM Breakwell, L Kornder, JM Pearce, SA Polasek, P Richardson, PM Grant, J Isaac, D Beresford, P Giannoccaro, P Roth, D Greenwood, P Muzyka, T Prosser, A Brass, N Hui, W Kvill, L Goeres, M MacDonald, K Senaratne, M Hill, L Humen, D Teo, KK Habib, N Habib, N Teekasingh, S MacKenzie, J McEwen, B Morris, A Dhair, A Lai, C Kwiatkowski, K Brugos, J Nawaz, S Andrews, J Moe, G Freskiw, K Gilbert, B Morgan, CD Bozek, B Halperin, F Ricci, AJ Singh, N Cappelli, G Boyne, T Fallen, E Panju, A Woodcock, G Kent, E Kitching, AD Sullivan, H Tomson, D McKelvie, RS Tsuyuki, RT Yusuf, S Chan, YK Thomson, D Arnold, JMO Hurwitz, G Miles, R Baker, A Haspect, A Smith, S Bedard, J Lavoie, L Dufort, L Harvey, R Lepage, S Elstein, E Fitchett, D Serpa, A Day, L Racine, N Savard, D Sestier, F Gosselin, G Rouleau, JL White, M Whittom, L Kiwan, G Kouz, SM Laforest, M Ouimet, H Carmichael, P Lenis, J Auger, P Grondin, F Saulnier, D Campeau, J Dupuis, R Lauzon, C Genest, M Robitaille, NM Beaudoin, J Belanger, N Houde, G Talbot, P Cossett, J Koilpillai, C Sheridan, WJ Tobin, M Sussex, B Ascoli, G Fraticelli, A Paciaroni, E Como, CO Belluschi, R Ruffa, F Tettamanti, F Cobelli, F Salvucci, F Arpesella, R Campana, C Gavazzi, A Cirrincione, V Ingrilli, F Sciortino, E Boccanelli, A Cacciatore, G Menichelli, M Bosimini, E Giannuzzi, P Marcassa, C Porcu, M Salis, S Sanna, A Comerio, G Gronda, E Mangiavacchi, M Moccetti, T Pasotti, E Sessa, F Levy, WC Probstfield, J Thompson, J Gramberg, M Grover, J Towery, D Ogunyankin, K Singh, BN Celano, J Graham, S Kohn, RM Pande, P Sass, A Wiener, RS Rydzinski, S Starling, RC Young, J Hays, L Naftilan, A Miller, A Varga, A Wofford, R Barnhill, S Brito, RD Harris, L Haspect, A Cristina, T Jarosz, M Kellen, J Kingry, C Letterer, R La Forge, D Liuni, C MacKenzie, J Magi, A Stevens, K Squires, P Yusuf, S Rouleau, JL Maggioni, A Arnold, JMO Avezum, A Burns, R Floras, J Gavazzi, A Held, P Hjalmarson, A Isaac, D Latini, R Lindgren, E McKelvie, RS Piegas, LS Pericak, D Pogue, J Probstfield, J Smith, S Swedberg, K Teo, KK Tsuyuki, RT Vint-Reed, C Wang, Y White, M Wiecek, EM Young, J Johnstone, D Armstrong, PW Packer, M Wedel, H Teo, KK Gavazzi, A Tsuyuki, RT White, M McKelvie, R Anderson, M Holadyk-Gris, I Kucemba, K MacKay, J McKelvie, RS Micks, M Pericak, D Pogue, J Reeve, S Robinson, L Tsuyuki, RT Tucker, J Wiecek, EM Wang, Y Yusuf, S Cernacek, P Joyal, M Poitras, N Rouleau, JL White, M Sirois, P Bevilacqua, M Latini, R Masson, S Torri, M Hall, C Burns, RJ Heeney, T Tadros, S White, M Yusuf, S McKelvie, RS Pericak, D Young, J Latini, R Pogue, J Burns, RJ Probstfield, J Tsuyuki, RT Maggioni, AP Avezum, A Rouleau, JL
Citation: W. Cirillo et al., Effects of metoprolol CR in patients with ischemic and dilated cardiomyopathy - The randomized evaluation of strategies for left ventricular dysfunction pilot study, CIRCULATION, 101(4), 2000, pp. 378-384
1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-L-erythro-pentofuran ose, a convenientprecursor for the stereospecific synthesis of nucleoside analogues with the unnatural beta-L-configuration
Authors: Mathe, C Imbach, JL Gosselin, G
Citation: C. Mathe et al., 1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-L-erythro-pentofuran ose, a convenientprecursor for the stereospecific synthesis of nucleoside analogues with the unnatural beta-L-configuration, CARBOHY RES, 323(1-4), 2000, pp. 226-229
Proceedings of the XIII International Round Table on Nucleosides, Nucleotides, and Their Biological Applications. Part II - Preface
Authors: Gosselin, G
Citation: G. Gosselin, Proceedings of the XIII International Round Table on Nucleosides, Nucleotides, and Their Biological Applications. Part II - Preface, NUCLEOS NUC, 18(6-7), 1999, pp. XXXIX-XL
A new and convenient approach for the synthesis of ribo- and 2 '-deoxyribo-beta-L-furanonucleosides starting from beta-L-xylofuranonucleosides
Authors: Boudou, V Gosselin, G Imbach, JL
Citation: V. Boudou et al., A new and convenient approach for the synthesis of ribo- and 2 '-deoxyribo-beta-L-furanonucleosides starting from beta-L-xylofuranonucleosides, NUCLEOS NUC, 18(4-5), 1999, pp. 607-609
3 '-(N-hydroxyimino)-2 ',3-dideoxynucleosides and their derivatives: Synthesis, broad spectrum antiviral properties and synthetical application for the preparation of other nucleoside analogues
Authors: Fedorov, I Kazmina, E Jasko, M Balzarini, J De Clercq, E Sommadossi, JP Imbach, JL Gosselin, G
Citation: I. Fedorov et al., 3 '-(N-hydroxyimino)-2 ',3-dideoxynucleosides and their derivatives: Synthesis, broad spectrum antiviral properties and synthetical application for the preparation of other nucleoside analogues, NUCLEOS NUC, 18(4-5), 1999, pp. 633-634
Stereospecific synthesis and antiviral activities of beta-L-2 ',3 '-dideoxy-5-chloropyrimidine nucleoside derivatives
Authors: Pierra, C Gosselin, G Sommadossi, JP Faraj, A De Clercq, E Balzarini, J Imbach, JL
Citation: C. Pierra et al., Stereospecific synthesis and antiviral activities of beta-L-2 ',3 '-dideoxy-5-chloropyrimidine nucleoside derivatives, NUCLEOS NUC, 18(4-5), 1999, pp. 643-644
Synthesis of new fluorescent nucleoside analogues and application to the study of human deoxycytidine kinase
Authors: Shafiee, M Gosselin, G Imbach, JL Eriksson, S Maury, G
Citation: M. Shafiee et al., Synthesis of new fluorescent nucleoside analogues and application to the study of human deoxycytidine kinase, NUCLEOS NUC, 18(4-5), 1999, pp. 717-719
Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy pyrimidine nucleoside triphosphates: Molecular basis for the combination of L-dideoxynucleoside analogs with nonnucleoside inhibitors in anti HIV chemotherapy.
Authors: Maga, G Amacker, M Hubscher, U Gosselin, G Imbach, JL Mathe, C Faraj, A Sommadossi, JP Spadari, S
Citation: G. Maga et al., Structural determinants of HIV-1 reverse transcriptase stereoselectivity towards (beta)-L-deoxy- and dideoxy pyrimidine nucleoside triphosphates: Molecular basis for the combination of L-dideoxynucleoside analogs with nonnucleoside inhibitors in anti HIV chemotherapy., NUCLEOS NUC, 18(4-5), 1999, pp. 795-805
Enzymatic preparation of P-32-labeled beta-L-2 ',3 '-dd-5 ' ATP and its use as a high-affinity, conformation-specific ligand for labeling adenylyl cyclases
Authors: Johnson, RA Shoshani, I Dessauer, C Gosselin, G
Citation: Ra. Johnson et al., Enzymatic preparation of P-32-labeled beta-L-2 ',3 '-dd-5 ' ATP and its use as a high-affinity, conformation-specific ligand for labeling adenylyl cyclases, NUCLEOS NUC, 18(4-5), 1999, pp. 839-842
Derivatives of L-adenosine and L-guanosine as substrates for human deoxycytidine kinase
Authors: Gaubert, G Gosselin, G Imbach, JL Eriksson, S Maury, G
Citation: G. Gaubert et al., Derivatives of L-adenosine and L-guanosine as substrates for human deoxycytidine kinase, NUCLEOS NUC, 18(4-5), 1999, pp. 857-860
Reasons and limits of substrate activity of modified L-dNTP in DNA biosynthesis
Authors: Krayevsky, AA Dyatkina, NB Semizarov, DG Victorova, LS Shirokova, EA Theil, F Lipinski, MV Gosselin, G Imbach, JL
Citation: Aa. Krayevsky et al., Reasons and limits of substrate activity of modified L-dNTP in DNA biosynthesis, NUCLEOS NUC, 18(4-5), 1999, pp. 863-864
Interaction of beta-L-adenosine-5 '-triphosphate (L-ATP) with human deoxycytidine kinase, human DNA primase and T4 DNA ligase: Does the chance directenzymatic enantioselectivity?
Authors: Verri, A Montecucco, A Gosselin, G Boudou, V Spadari, S Imbach, JL Focher, F
Citation: A. Verri et al., Interaction of beta-L-adenosine-5 '-triphosphate (L-ATP) with human deoxycytidine kinase, human DNA primase and T4 DNA ligase: Does the chance directenzymatic enantioselectivity?, NUCLEOS NUC, 18(4-5), 1999, pp. 867-869
ddC- and 3TC-bis(SATE) monophosphate prodrugs overcome cellular resistancemechanisms to HIV-1 associated with cytidine kinase deficiency
Authors: Groschel, B Himmel, N Cinatl, J Perigaud, C Gosselin, G Imbach, JL Doerr, HW Cinatl, J
Citation: B. Groschel et al., ddC- and 3TC-bis(SATE) monophosphate prodrugs overcome cellular resistancemechanisms to HIV-1 associated with cytidine kinase deficiency, NUCLEOS NUC, 18(4-5), 1999, pp. 921-926
Prodrugs of Ara-CMP and Ara-AMP with a S-acyl-2-thioethyl (SATE) biolabilephosphate protecting group: Synthesis and biological evaluation
Authors: Bazzanini, R Manfredini, S Durini, E Groschel, B Cinatl, J Balzarini, J De Clercq, E Imbach, JL Perigaud, C Gosselin, G
Citation: R. Bazzanini et al., Prodrugs of Ara-CMP and Ara-AMP with a S-acyl-2-thioethyl (SATE) biolabilephosphate protecting group: Synthesis and biological evaluation, NUCLEOS NUC, 18(4-5), 1999, pp. 971-972
Anti-HIV pronucleotides: Sate versus phenyl as a protecting grow of AZT phosphoramidate derivatives
Authors: Beltran, T Egron, D Lefebvre, I Perigaud, C Pompon, A Gosselin, G Aubertin, AM Imbach, JL
Citation: T. Beltran et al., Anti-HIV pronucleotides: Sate versus phenyl as a protecting grow of AZT phosphoramidate derivatives, NUCLEOS NUC, 18(4-5), 1999, pp. 973-975
Synthesis and anti-HIV activity of some S-acyl-2-thioethyl (SATE) phosphoramidate derivatives of 3 '-azido-2 ',3 '-dideoxythymidine
Authors: Egron, D Perigaud, C Gosselin, G Aubertin, AM Imbach, JL
Citation: D. Egron et al., Synthesis and anti-HIV activity of some S-acyl-2-thioethyl (SATE) phosphoramidate derivatives of 3 '-azido-2 ',3 '-dideoxythymidine, NUCLEOS NUC, 18(4-5), 1999, pp. 981-982
Synthesis, anti-HIV activity and stability studies of 3 '-azido-2 ',3 '-dideoxythymidine 5 '-fluorophosphate
Authors: Egron, D Arzumanov, AA Dyatkina, NB Krayevsky, A Imbach, JL Aubertin, AM Gosselin, G Perigaud, C
Citation: D. Egron et al., Synthesis, anti-HIV activity and stability studies of 3 '-azido-2 ',3 '-dideoxythymidine 5 '-fluorophosphate, NUCLEOS NUC, 18(4-5), 1999, pp. 983-984
Intracellular metabolism of beta-L-ddAMP-bis(tbutylSATE), a potent inhibitor of hepatitis B virus replication
Authors: Faraj, A Placidi, L Perigaud, C Cretton-Scott, E Gosselin, G Martin, LT Pierra, C Schinazi, RF Imbach, JL Sommadossi, JP
Citation: A. Faraj et al., Intracellular metabolism of beta-L-ddAMP-bis(tbutylSATE), a potent inhibitor of hepatitis B virus replication, NUCLEOS NUC, 18(4-5), 1999, pp. 987-988
Synthesis and in vitro antiviral activity of some symmetrical phosphoramidate dimers of AZT
Authors: Kers, I Girardet, JL Gosselin, G Perigaud, C Imbach, JL Stawinski, J
Citation: I. Kers et al., Synthesis and in vitro antiviral activity of some symmetrical phosphoramidate dimers of AZT, NUCLEOS NUC, 18(4-5), 1999, pp. 993-994
Risultati: 1-25 | 26-50 | 51-72