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Results: 1-22 |
Results: 22
Preparation of oligonucleotides without aldehyde abasic sites
Authors: Krotz, AH Gaus, H Ravikumar, VT Cole, DL
Citation: Ah. Krotz et al., Preparation of oligonucleotides without aldehyde abasic sites, BIOORG MED, 11(14), 2001, pp. 1863-1867
Applications of green chemistry in the manufacture of oligonucleotide drugs
Authors: Sanghvi, YS Ravikumar, VT Scozzari, AN Cole, DL
Citation: Ys. Sanghvi et al., Applications of green chemistry in the manufacture of oligonucleotide drugs, PUR A CHEM, 73(1), 2001, pp. 175-180
Influence of diastereomeric ratios of deoxyribonucleoside phosphoramiditeson the synthesis of phosphorothioate oligonucleotides
Authors: Cheruvallath, ZS Sasmor, H Cole, DL Ravikumar, VT
Citation: Zs. Cheruvallath et al., Influence of diastereomeric ratios of deoxyribonucleoside phosphoramiditeson the synthesis of phosphorothioate oligonucleotides, NUCLEOS NUC, 19(3), 2000, pp. 533-543
Pyridinium trifluoroacetate/N-methylimidazole as an efficient activator for oligonucleotide synthesis via the phosphoramidite method
Authors: Eleuteri, A Capaldi, DC Krotz, AH Cole, DL Ravikumar, VT
Citation: A. Eleuteri et al., Pyridinium trifluoroacetate/N-methylimidazole as an efficient activator for oligonucleotide synthesis via the phosphoramidite method, ORG PROC R, 4(3), 2000, pp. 182-189
Large-scale synthesis of antisense oligonucleotides without chlorinated solvents
Authors: Krotz, AH Carty, RL Scozzari, AN Cole, DL Ravikumar, VT
Citation: Ah. Krotz et al., Large-scale synthesis of antisense oligonucleotides without chlorinated solvents, ORG PROC R, 4(3), 2000, pp. 190-193
Synthesis of antisense oligonucleotides: Replacement of 3H-1,2-benzodithiol-3-one 1,1-dioxide (Beaucage reagent) with phenylacetyl disulfide (PADS) as efficient sulfurization reagent: From bench to bulk manufacture of activepharmaceutical ingredient
Authors: Cheruvallath, ZS Carty, RL Moore, MN Capaldi, DC Krotz, AH Wheeler, PD Turney, BJ Craig, SR Gaus, HJ Scozzari, AN Cole, DL Ravikumar, VT
Citation: Zs. Cheruvallath et al., Synthesis of antisense oligonucleotides: Replacement of 3H-1,2-benzodithiol-3-one 1,1-dioxide (Beaucage reagent) with phenylacetyl disulfide (PADS) as efficient sulfurization reagent: From bench to bulk manufacture of activepharmaceutical ingredient, ORG PROC R, 4(3), 2000, pp. 199-204
A liquid-phase process suitable for large-scale synthesis of phosphorothioate oligonucleotides
Authors: Bonora, GM Rossin, R Zaramella, S Cole, DL Eleuteri, A Ravikumar, VT
Citation: Gm. Bonora et al., A liquid-phase process suitable for large-scale synthesis of phosphorothioate oligonucleotides, ORG PROC R, 4(3), 2000, pp. 225-231
Synthesis of antisense oligonucleotides using environmentally friendly andsafe deprotection procedures
Authors: Krotz, AH Carty, RL Moore, MN Scozzari, AN Cole, DL Ravikumar, VT
Citation: Ah. Krotz et al., Synthesis of antisense oligonucleotides using environmentally friendly andsafe deprotection procedures, GREEN CHEM, 1(6), 1999, pp. 277-281
Is it essential to use anhydrous acetonitrile in the manufacture of phosphorothioate oligonucleotides?
Authors: Capaldi, DC Scozzari, AN Cole, DL Ravikumar, VT
Citation: Dc. Capaldi et al., Is it essential to use anhydrous acetonitrile in the manufacture of phosphorothioate oligonucleotides?, ORG PROC R, 3(6), 1999, pp. 485-487
Synthesis of an antisense oligonucleotide targeted against C-raf kinase: Efficient oligonucleotide synthesis without chlorinated solvents
Authors: Krotz, AH Cole, DL Ravikumar, VT
Citation: Ah. Krotz et al., Synthesis of an antisense oligonucleotide targeted against C-raf kinase: Efficient oligonucleotide synthesis without chlorinated solvents, BIO MED CH, 7(3), 1999, pp. 435-439
Synthesis of dimer phosphoramidite synthons for oligodeoxyribonucleotide phosphorothioates using diethyldithiocarbonate disulfide as an efficient sulfurizing reagent
Authors: Eleuteri, A Cheruvallath, ZS Capaldi, DC Cole, DL Ravikumar, VT
Citation: A. Eleuteri et al., Synthesis of dimer phosphoramidite synthons for oligodeoxyribonucleotide phosphorothioates using diethyldithiocarbonate disulfide as an efficient sulfurizing reagent, NUCLEOS NUC, 18(8), 1999, pp. 1803-1807
Efficient synthesis of deoxyribonucleoside phosphoramidites by eliminatingthe use of additional activator
Authors: Eleuteri, A Capaldi, DC Cole, DL Ravikumar, VT
Citation: A. Eleuteri et al., Efficient synthesis of deoxyribonucleoside phosphoramidites by eliminatingthe use of additional activator, NUCLEOS NUC, 18(8), 1999, pp. 1879-1882
Stability of phosphorothioate oligonucleotides in aqueous ammonia in presence of stainless steel
Authors: Turney, BJ Cheruvallath, ZS Andrade, M Cole, DL Ravikumar, VT
Citation: Bj. Turney et al., Stability of phosphorothioate oligonucleotides in aqueous ammonia in presence of stainless steel, NUCLEOS NUC, 18(6-7), 1999, pp. 1187-1189
Diastereomeric process control in the synthesis of oligodeoxyribonucleotide phosphorothioates
Authors: Cheruvallath, ZS Wyrzykiewicz, TK Cole, DL Ravikumar, VT
Citation: Zs. Cheruvallath et al., Diastereomeric process control in the synthesis of oligodeoxyribonucleotide phosphorothioates, NUCLEOS NUC, 18(6-7), 1999, pp. 1191-1194
Use of phenylacetyl disulfide (PADS) in the synthesis of oligodeoxyribonucleotide phosphorothioates
Authors: Cheruvallath, ZS Wheeler, PD Cole, DL Ravikumar, VT
Citation: Zs. Cheruvallath et al., Use of phenylacetyl disulfide (PADS) in the synthesis of oligodeoxyribonucleotide phosphorothioates, NUCLEOS NUC, 18(6-7), 1999, pp. 1195-1197
Dimethoxytrityl removal in organic medium: Efficient oligonucleotide synthesis without chlorinated solvents
Authors: Krotz, AH Cole, DL Ravikumar, VT
Citation: Ah. Krotz et al., Dimethoxytrityl removal in organic medium: Efficient oligonucleotide synthesis without chlorinated solvents, NUCLEOS NUC, 18(6-7), 1999, pp. 1207-1209
Oligodeoxyribonucleotide phosphorothioates: Substantial reduction of (N-1)-mer content through the use of blockmer phosphoramidite synthons
Authors: Eleuteri, A Cheruvallath, ZS Capaldi, DC Krotz, AH Cole, DL Ravikumar, VT
Citation: A. Eleuteri et al., Oligodeoxyribonucleotide phosphorothioates: Substantial reduction of (N-1)-mer content through the use of blockmer phosphoramidite synthons, NUCLEOS NUC, 18(6-7), 1999, pp. 1211-1213
Synthesis of deoxyribonucleoside phosphorodithioate dimers by a triester method
Authors: Capaldi, DC Cole, DL Ravikumar, VT
Citation: Dc. Capaldi et al., Synthesis of deoxyribonucleoside phosphorodithioate dimers by a triester method, NUCLEOS NUC, 18(6-7), 1999, pp. 1215-1217
Oligodeoxyribonucleotide phosphorothioates: Substantial reduction of (n-1)-mer content through the use of trimeric phosphoramidite synthons
Authors: Eleuteri, A Capaldi, DC Cole, DL Ravikumar, VT
Citation: A. Eleuteri et al., Oligodeoxyribonucleotide phosphorothioates: Substantial reduction of (n-1)-mer content through the use of trimeric phosphoramidite synthons, NUCLEOS NUC, 18(3), 1999, pp. 475-483
Use of phenylacetyl disulfide (PADS) in the synthesis of oligodeoxyribonucleotide phosphorothioates
Authors: Cheruvallath, ZS Wheeler, PD Cole, DL Ravikumar, VT
Citation: Zs. Cheruvallath et al., Use of phenylacetyl disulfide (PADS) in the synthesis of oligodeoxyribonucleotide phosphorothioates, NUCLEOS NUC, 18(3), 1999, pp. 485-492
Stability of phosphorothioate oligonucleotides in aqueous ammonia in presence of stainless steel
Authors: Turney, BJ Cheruvallath, ZS Andrade, M Cole, DL Ravikumar, VT
Citation: Bj. Turney et al., Stability of phosphorothioate oligonucleotides in aqueous ammonia in presence of stainless steel, NUCLEOS NUC, 18(1), 1999, pp. 89-93
5-chlorophenyl phosphorodichloridothioate
Authors: Ravikumar, VT Ross, B
Citation: Vt. Ravikumar et B. Ross, 5-chlorophenyl phosphorodichloridothioate, ORG SYNTH, 76, 1999, pp. 271-274
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